Corpus callosum là gì

What is agenesis of the corpus callosum?

The corpus callosum is a part of the brain. Its nerve sầu fibers connect the two sides (cerebral hemispheres) of the brain. Agenesis of the corpus callosum is a birth defect that happens when this structure does not develop properly.

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There is a broad range of outcomes for babies born with agenesis of the corpus callosum, ranging from essentially normal function in the mildest cases lớn a range of potential health and developmental problems as severity increases.

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Learn more about our Prenatal Pediatrics Institute.

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In many cases, we cannot identify the cause of agenesis of the corpus callosum. Known causes include:

Chromosomal defects that affect fetal brain development Certain viral infections in the mother that pass lớn the developing baby Exposure of the unborn baby to lớn certain toxins or medications Abnormal brain development caused by cysts

If there are no other brain development abnormalities, infants may have few, if any, significant difficulties in later life. Newborns with agenesis of the corpus callosum may not show symptoms right away, especially if they have sầu no other associated conditions. Comtháng symptoms that may become more apparent during infancy and childhood include:

Cognitive sầu impairment Poor feeding và difficulty swallowing Developmental delays in motor và language skills such as sitting up, walking & talking Vision và hearing impairment Poor muscle tone and coordination Insomnia or other sleep problems Psychosocial difficulties including attention deficit disorder (ADD), obsessive sầu behaviors & social immaturity Cognitive sầu difficulties including learning disabilities & problems with abstract thinking và problem solving

Your physician may suspect agenesis of the corpus callosum based on routine prenatal ultrasoundexams performed during pregnancy. Your doctor may refer you lớn our Prenatal Pediatrics Institutefor further testing khổng lồ evaluate your baby’s condition. Tests may include:

High-resolution (level II) ultrasound to lớn confirm the diagnosis Fetal MRI to help confirm the diagnosis and identify whether associated brain problems are present. This advanced, high-resolution imaging test gives the best information about the underlying cause and the best picture of the rest of the baby’s brain. MRI after birth to provide further information of your baby What are treatments for agenesis of the corpus callosum?

Currently, there are no treatments lớn restore the corpus callosum lớn normal. The main course of treatment for agenesis of the corpus callosum is to lớn manage any complications that may arise. Treatment options may include:

Medications lớn control seizures Occupational therapy khổng lồ help build self-care and mobility skills such as eating, getting dressed & walking

Sadie"s Story


Sadie is one of hundreds of infants with axinh đẹp encephalopathy who have sầu received whole-body therapeutic hypothermia at the Children"s National neonatal intensive care unit. Whole-body toàn thân therapeutic hypothermia is offered in the first few hours of life khổng lồ preserve brain cells & khổng lồ stave off disability or death.

Chuyên mục: Giải Đáp